Tools for Fluorescence-based Apoptosis and Caspase Detection

Apoptosis is an evolutionarily conserved form of cell suicide responsible for various biological processes including the normal turnover of cells and the proper functioning of the immune system.  This process of shutting down old, diseased, or otherwise disfunctional cells is mediated by a cascade of proteolytic enzymes known as cysteine proteases, or caspases. Pro-apoptotic signals activate the enzymatic cascade resulting in the cleavage of protein substrates, leading to the disassembly of the cell (1-4). Caspases have been identified in organisms ranging from C. elegans to humans. Members of the

Featured Summer Citations for Apoptosis, Caspase, and Cathepsin Detection

Our fluorescent protease detection probes continue to be routinely referenced in customers' publications. Here are a few of the latest:

Neuronal toxicity assessed by SR-FLIVO™: Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease

Image Apoptosis In Vivo! NIR-FLIVO Tracers Now Available

ImmunoChemistry Technologies, LLC is pleased to announce the launch of two new tracers for non-invasive in vivo optical imaging of apoptosis. NIR-FLIVO™ 690 and NIR-FLIVO™ 747 in vivo apoptosis tracers and free dye control reagents are now available from ImmunoChemistry Technologies at introductory pricing.

New FLICA Caspase Assay Citations from Korean Research Institutes

Congratulations to our FLICA caspase assay customers at several research institutes in the Republic of Korea for publishing recent studies!

From Gyeongsang National University:

Aged Red Garlic Extract Reduces Cigarette Smoke Extract-induced Cell Death in Human Bronchial Smooth Muscle Cells by Increasing Intracellular Glutathione Levels

Yi-Yeong Jeong, Hye-Jin Park, Young-Woo Cho, Eun-Jin Kim, Gyu-Tae Kim, Yun-Ja Mun, Jong Deog Lee, Jung-Hye Shin, Nak-Ju Sung, Dawon Kang, Jaehee Han

Federal Qualified Therapeutic Discovery Project Grants Awarded to ICT

Bloomington, MN, November 1, 2010 - ImmunoChemistry Technologies announced that they will receive two Qualifying Therapeutic Discovery Project Grants from the IRS in conjunction with the U.S. Department of Health and Human Services.

New Products: Affipure Goat HRP-Anti-IgG Secondaries

Affipure Goat HRP-Anti-IgG Secondaries for all ELISA formats and Western blotting are now available from ICT:

• HRP Goat anti-Human IgG Fc
• HRP Goat anti-Rabbit IgG Fc
• HRP Goat anti-Mouse IgG Fc

ICT's new online home has launched!

On September 17, 2010, ICT launched a completely new design on our website, immunochemistry.com. We added new features, such as a document library, instant credit card processing for product orders, and in-depth information about our assay development and custom laboratory services.