Researchers at Harvard Medical School and Schepens Eye Research Institute recently published a study using several of our FLICA apoptosis assays to detect caspase activity in retinal pigment epithelial cells.
Kim LA., Amarnani D, Gnanaguru G, Tsen WA, Vavvas DG, and D'Amore PA. (2014.) Tamoxifen Toxicity in Cultured Retinal Pigment Epithelial Cells Is Mediated by Concurrent Regulated Cell Death Mechanisms. Invest. Ophthalmol. Vis. Sci., 55(8), 4747-4758. [Abstract]
Kim LA., Amarnani D, Gnanaguru G, Tsen WA, Vavvas DG, and D'Amore PA. (2014.) Tamoxifen Toxicity in Cultured Retinal Pigment Epithelial Cells Is Mediated by Concurrent Regulated Cell Death Mechanisms. Invest. Ophthalmol. Vis. Sci., 55(8), 4747-4758. [Abstract]
"Caspase activity was evaluated by caspase-1, -3, -8, and -9 specific inhibition... Caspase activity was verified with the fluorochrome-labeled inhibitor of caspases (FLICA) probe specific for each caspase."
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