Following a low pH and H2O2 treatment, keratoconus fibroblast cultures (right) exhibit higher levels of caspase-3 activity than normal cultures (left) via staining with FAM-FLICA caspase 3 assay (green caspase 3 inhibitor probe, FAM-DEVD-FMK). Data courtesy of Drs. Kenney and Luthra, University of California Irvine Medical Center.
