Study Reveals Kinetics in Turnover of Young Rat Urothelium, Employing FAM-FLIVO™ for in vivo Apoptosis Detection

The recently published study by Erman et. al. (Apoptosis and Desquamation of Urothelial Cells in Tissue Remodeling During Rat Postnatal Development, J. Histochem. Cytochem. 57(8):721-730, 2009) used ImmunoChemistry Technologies’ FAM-FLIVO reagent (catalog #981) to observe the levels of apoptosis in urothelial cells of the young rat bladder. The study clearly demonstrates the kinetics in turnover of rat urothelium in the early postnatal period (birth to day 14) evidenced by apoptosis, autophagic cell death, and desquamation.