First FLICA 660 Caspase-1 Assay Citations

THP-1 cells with activated caspase-1 enzyme (ICE) emit far-red
fluorescence after staining with FLICA 660 Caspase-1 Assay

Recent peer-reviewed articles in Journal of Hepatology and Journal of Leukocyte Biology validate the use of the new FLICA® 660 Caspase-1 Assay Kit for caspase-1 detection.

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation and fibrosis

Wree A, Eguchi A, McGeough M, Pena CA, Johnson CD, Canbay A, Hoffman HM, Feldstein AE, et al.
J Hepatol doi:10.1002/hep.26592
First published online: 2013 [Abstract]

"Active Caspase 1 was measured in parenchymal cell suspensions with FLICA 660-YVAD-FMK (FLICA® 660 in vitro Active Caspase-1 Detection Kit, ImmunoChemistry Technologies, Bloomington, MN,  USA) according to manufactures [sic] instructions and with propidium iodide (PI) to mark cells with membrane pores..."

Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen

Miles B, Scisci E, Carrion J, Sabino GJ, Genco CA, Cutler CW, et al.
J. Leukocyte Biol doi:10.1189/jib.0213108
First Published Online: May 31, 2013

"Intracellular polycaspase, initiator caspase-3/7, and effector caspase-1 and -8 were determined using ... and FLICA 660 Caspase-1 kit (9122, ImmunoChemistry Technologies, Bloomington, MN, USA), according to the manufacturer's instructions."

Read more about our new far-red fluorescent FLICA 660 Caspase-1 Assay Kit (cat. no. 9122) for activated caspase-1 detection using flow cytometry and fluorescence microscopy.






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